Springer Exemplar

... Background MCT-1 oncoprotein accelerates	p53 Molecular Cancer The antagonism between MCT-1 and p53 affects the tumorigenic outcomes Kasiappan, Ravi; Shih, Hung-Ju; Wu, Meng-Hsun; Choy, ChikOn; Lin, Tai-Du; Chen, Linyi; Hsu, Hsin-Ling	protein degradation via a proteosome pathway. ...
... The	p53 Signaling Pathways in Liver Diseases p53 Tsai, Wen-Wei; Barton, Michelle Craig	tumor suppressor is well known as the major ...
... Mutations in the TP53 gene or the	p53 CNS Cancer p53 Pathway Alterations in Brain Tumors Yin, Shaoman; Van Meir, Erwin G.	pathway are required for the formation of many ...
... by this role of nucleoli is the tumor suppressor	p53 Cellular and Molecular Life Sciences Nucleolar control of p53: a cellular Achilles’ heel and a target for cancer therapy Vlatković, Nikolina; Boyd, Mark T.; Rubbi, Carlos P.	, which is activated in response to diverse ...
... Most tumors inactivate the	p53 p53 in the Clinics Mutant p53-Driven Tumorigenesis Terzian, Tamara; Lozano, Guillermina	tumor suppressor pathway via single nucleotide ...
... Reinstatement of the	p53 p53 in the Clinics p53-Reactivating Molecules as Research Tools and Anticancer Drugs Grinkevich, Vera V.; Warnecke, Andreas; Selivanova, Galina	tumor suppressor function in cancers by small ...
... Understanding the mechanism underlying	p53 Journal of Neuro-Oncology Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes Amano, Toshiyuki; Nakamizo, Akira; Mishra, Sandip K.; Gumin, Joy; Shinojima, Naoki; Sawaya, Raymond; Lang, Frederick F.	’s ability to induce cell cycle arrest versus ...
...	p53 Cell Senescence Senescence Regulation by the p53 Protein Family Qian, Yingjuan; Chen, Xinbin	, a guardian of the genome, exerts its tumor ...
...	p53 Signal Transduction: Pathways, Mechanisms and Diseases Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis Giono, Luciana E.; Manfredi, James J.	is a widely conserved tumor suppressor protein ...
...	p53 Apoptosis Targeting p53 for enhanced radio- and chemo-sensitivity Lu, Chao; El-Deiry, Wafik S.	acts as a central mediator of the cellular ...
... Background The tumor suppressor gene	p53 Molecular Cancer Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters Baumbusch, Lars; Myhre, Simen; Langerød, Anita; Bergamaschi, Anna; Geisler, Stephanie; Lønning, Per; Deppert, Wolfgang; Dornreiter, Irene; Børresen-Dale, Anne-Lise	(TP53) controls numerous signaling pathways and ...
...	p53 25 Years of p53 Research Regulation of p53 DNA Binding McKinney, Kristine; Prives, Carol	is one of the most frequently mutated genes in ...
... The	p53 Lung Cancer Clinical Implications of p53 Mutations in Lung Cancer Campling, Barbara G.; El-Deiry, Wafik S.	tumor-suppressor gene plays a crucial role in the ...
... No summary available 1 The	p53 Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy p53 Inhibitors as Cancer Sensitizing Agents Maina, Flavio; Dono, Rosanna	Player: A Stage Director for the Fate of Stressed ...
... Introduction Normal function of the	p53 Breast Cancer Research p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients Bourdon, Jean-Christophe; Khoury, Marie P; Diot, Alexandra; Baker, Lee; Fernandes, Kenneth; Aoubala, Mustapha; Quinlan, Philip; Purdie, Colin A; Jordan, Lee B; Prats, Anne-Catherine; Lane, David P; Thompson, Alastair M	network is lost in most cancers, often through ...
... Background The	p53 Biology Direct Impact of Alu repeats on the evolution of human p53 binding sites Cui, Feng; Sirotin, Michael V; Zhurkin, Victor B	tumor suppressor protein is involved in a ...
... In this work we present evidence that the	p53 BMC Immunology Modulation of p53 activity by IκBα: Evidence suggesting a common phylogeny between NF-κB and p53 transcription factors Dreyfus, David; Nagasawa, Masayuki; Gelfand, Erwin; Ghoda, Lucy	tumor suppressor protein and NF-κB transcription ...
... Happy 25th Anniversary	p53 25 Years of p53 Research Gatekeepers of the Guardian: p53 Regulation by Post-Translational Modification, MDM2 and MDMX Wahl, Geoffrey M.; Stommel, Jayne M.; Krummel, Kurt; Wade, Mark	! Since this is such a special occasion, I (GW) ...
... Single mutations in the DNA binding domain of	p53 The p53 Tumor Suppressor Pathway and Cancer The Oncogenic Activity of p53 Mutants Sigal, Alex; Rotter, Varda	cause a radical shift in function from tumor ...
... The	p53 The p53 Tumor Suppressor Pathway and Cancer p53 in Human Cancer — Somatic and Inherited Mutations and Mutation-independent Mechanisms Moll, Ute M.; Concin, Nicole	tumor suppressor protein plays a central role in ...
... The best-characterized function of	p53 The p53 Tumor Suppressor Pathway and Cancer Transcriptional Activation by p53: Mechanisms and Targeted Genes MacLachlan, Timothy; El-Deiry, Wafik	, the most renowned tumor suppressor, is that of ...
... The	p53 Cancer and Metastasis Reviews The p53 protein family and radiation sensitivity: Yes or no? Cuddihy, Andrew R.; Bristow, Robert G.	tumor suppressor protein is a key mediator of an ...
...	p53 Journal of Molecular Medicine Exonucleolytic degradation of RNA by p53 protein in cytoplasm Bakhanashvili, Mary; Gedelovich, Rachel; Grinberg, Shai; Rahav, Galia	in cytoplasm displays an intrinsic 3′→5′ ...
... of the Forkhead box (Fox; Sect. 10.9.3) and	P53 Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems Other Major Types of Signaling Mediators Thiriet, Marc	families (Sect. 10.9.4; Table 10.1). Other ...
... The human mutant	p53 Transgenic Research Lung specific expression of a human mutant p53 affects cell proliferation in transgenic mice Duan, Wenrui; Gao, Li; Jin, David; Otterson, Gregory A.; Villalona-Calero, Miguel A.	(273H) has been shown in vitro to have both ...

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