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... rate results in nucleolar stress activation of  p53 
The Role of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Embryonic Neural Crest Cells and Their Derivatives
The Role of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Embryonic Neural Crest Cells and Their Derivatives
Kalev-Altman, Rotem; Monsonego-Ornan, Efrat; Sela-Donenfeld, Dalit
which in turn transcriptionally activates ...
... In replicating β cells the NO effect may involve  p53 
Preventing Type 1 Diabetes Mellitus
Preventing Type 1 Diabetes Mellitus
Efrat, Shimon
, a key intracellular regulator of apoptosis.[26] ...
... proteins Bcl-2 and Bcl-XL and stimulates  p53 
Reversal effect of ouabain on multidrug resistance in esophageal carcinoma EC109/CDDP cells by inhibiting the translocation of Wnt/β-catenin into the nucleus
Reversal effect of ouabain on multidrug resistance in esophageal carcinoma EC109/CDDP cells by inhibiting the translocation of Wnt/β-catenin into the nucleus
Shen, Yucheng; Wang, Qinghua; Tian, Ye
phosphorylation. ...
... cell carcinomas. These include the induction of  p53 
Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
Yang, David T; Young, Ken H; Kahl, Brad S; Markovina, Stephanie; Miyamoto, Shigeki
, mouse double minute 2, p21, and p27; ...
... [23]. Als Zielstrukturen wurden unter anderem  p53 
Immunmodulation als innovative Therapie bei Kopf-Hals-Tumoren
Immunmodulation als innovative Therapie bei Kopf-Hals-Tumoren
Schuler, P. J.; Doescher, J. C.; Laban, S.; Hoffmann, T. K.
[22], Tumorlysat [13], MAGE („melanoma-associated ...
... that miR-149 could be directly upregulated by  p53 
Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk
Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk
Fan, Xiaohong; Wu, Zhijun
that in turn targeted glycogen synthase ...
... al. 2015). TLR8 rs3761624 SNP, localized in the  p53 
TLR8
TLR8
Cervantes, Jorge; Maulén, Nancy; Chai, Han-Ha
response element of the TLR8 promoter region, ...
... membrane and the whole process in independent on  p53 
Wnt signaling in regulation of biological functions of the nurse cell harboring Trichinella spp.
Wnt signaling in regulation of biological functions of the nurse cell harboring Trichinella spp.
Dabrowska, Magdalena; Skoneczny, Marek; Zielinski, Zbigniew; Rode, Wojciech
suppressor gene [2, 27, 28]. ...
... Patienten häufig Mutationen im Tumorsuppressor  p53 
Epidemiologie und molekulare Pathogenese des hepatozellulären Karzinoms
Epidemiologie und molekulare Pathogenese des hepatozellulären Karzinoms
Vogel, A.; Manns, M.P.
finden. ...
... mediates ubiquitination and degradation of the  p53 
The prevalence of human papillomavirus in oral premalignant lesions and squamous cell carcinoma in comparison to cervical lesions used as a positive control
The prevalence of human papillomavirus in oral premalignant lesions and squamous cell carcinoma in comparison to cervical lesions used as a positive control
Ishibashi, Miki; Kishino, Mitsunobu; Sato, Sunao; Morii, Eiichi; Ogawa, Yuzo; Aozasa, Katsuyuki; Kogo, Mikihiko; Toyosawa, Satoru
tumour suppressor protein [16, 17]. ...
... the apoptosis pathway by stimulation of Bax,  p53 
Propolis: a new frontier for wound healing?
Propolis: a new frontier for wound healing?
Martinotti, Simona; Ranzato, Elia
, p21 proteins, p38 MAPK, JNK, ERK kinases, ...
... CREB iNOS/eNOS VEGF/KDR DR4/DR5 TRAIL  P53 
Grape Polyphenols in the Prevention of Cardiovascular Disease
Grape Polyphenols in the Prevention of Cardiovascular Disease
Gross, Myron
/p21Cip1 Sir2 NK-κB/AP-1 IGF-1 ...
... has been recently proposed as a direct target of  p53 
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
Puig, Teresa; Aguilar, Helena; Cufí, Sílvia; Oliveras, Glòria; Turrado, Carlos; Ortega-Gutiérrez, Sílvia; Benhamú, Bellinda; López-Rodríguez, María Luz; Urruticoechea, Ander; Colomer, Ramon
family members, including p63 and p73 [22]. ...
... DNA binding sites for tumor suppressor protein  p53 
Inhibition of CD200R1 expression by C/EBP beta in reactive microglial cells
Inhibition of CD200R1 expression by C/EBP beta in reactive microglial cells
Dentesano, Guido; Straccia, Marco; Ejarque-Ortiz, Aroa; Tusell, Josep M; Serratosa, Joan; Saura, Josep; Solà, Carme
, a critical regulator of the apoptotic program, ...
... also retrieved in our predicted list: CREB, OCT,  P53 
Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy
Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy
Qian, Kui; Lieto, Antonio; Corander, Jukka; Auvinen, Petri; Greco, Dario
, SP1, TATA, ATF4 and MYC [51,  52,  53,  54,  ...
... These events were associated with induction of  p53 
Identification of IMPDH2 as a tumor-associated antigen in colorectal cancer using immunoproteomics analysis
Identification of IMPDH2 as a tumor-associated antigen in colorectal cancer using immunoproteomics analysis
He, Yujun; Mou, Zhirong; Li, Wanlin; Liu, Baohua; Fu, Tao; Zhao, Shong; Xiang, Debing; Wu, Yuzhang
activity, cell growth inhibition, cell cycle ...
... biomarkers, such as the tumor suppressor gene  p53 
Use Case III: Imaging Biomarkers in Breast Tumours. Development and Clinical Integration
Use Case III: Imaging Biomarkers in Breast Tumours. Development and Clinical Integration
Marino, M. A.; Pinker, K.; Baltzer, P.; Helbich, T. H.
and claudin, a protein involved in the harmonious ...
... possibly due to the mislocalization of  p53 
ING4 is negatively correlated with microvessel density in colon cancer
ING4 is negatively correlated with microvessel density in colon cancer
Lou, Chun; Jiang, Shixiong; Guo, Xinggang; Dong, Xin-shu
and/or HAT/HDAC complexes [40]. ...
... in cancer cells with nonsense mutations in the  p53 
Control of gene expression through the nonsense-mediated RNA decay pathway
Control of gene expression through the nonsense-mediated RNA decay pathway
Nickless, Andrew; Bailis, Julie M.; You, Zhongsheng
gene [157, 158]. ...
... which was dependent on the relative levels of  p53 
Cell Competition and the Hippo Pathway
Cell Competition and the Hippo Pathway
Chen, Chiao-Lin; Halder, Georg
. ...
... structures (Fig. 3b). This lectin, also called  p53 
Galectins as tools for glycan mapping in histology: comparison of their binding profiles to the bovine zona pellucida by confocal laser scanning microscopy
Galectins as tools for glycan mapping in histology: comparison of their binding profiles to the bovine zona pellucida by confocal laser scanning microscopy
Habermann, Felix A.; André, Sabine; Kaltner, Herbert; Kübler, Dieter; Sinowatz, Fred; Gabius, Hans-Joachim
-induced gene 1, can in principle home in on ...
... 1 7040 21803 59086 10 10 10 30 TP53 tumor protein  p53 
Extracting unrecognized gene relationships from the biomedical literature via matrix factorizations
Extracting unrecognized gene relationships from the biomedical literature via matrix factorizations
Kim, Hyunsoo; Park, Haesun; Drake, Barry L
(Li-Fraumeni syndrome) 7157 22059 24842 10 10 10 ...
... to exhibit transforming activity and bind to  p53 
Detection of human herpesvirus-6 in adult central nervous system tumors: predominance of early and late viral antigens in glial tumors
Detection of human herpesvirus-6 in adult central nervous system tumors: predominance of early and late viral antigens in glial tumors
Crawford, John R.; Santi, Maria Rita; Cornelison, Robbie; Sallinen, Satu-Leena; Haapasalo, Hannu; MacDonald, Tobey J.
[39, 40]. ...
... of N1ICD has been reported to inhibit wild-type  p53 
The cytotoxicity of γ-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by γ-secretase inhibition
The cytotoxicity of γ-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by γ-secretase inhibition
Han, Jianxun; Ma, Ivy; Hendzel, Michael J; Allalunis-Turner, Joan
-induced apoptosis in immortalized epidermal ...
... pathologists, or if accompanied by aberrant  p53 
Oesophagus
Oesophagus
McManus, Damian T.; Allen, Derek C.; Cameron, R. Iain
staining or abnormal DNA content. ...

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